Anti-tTG IgA | Antibodies against tissue transglutaminase (in adults for testing for celiac disease)

Adults are tested for: antibodies against tissue transglutaminase Anti-tTG IgA and IgG.

Celiac disease is an autoimmune, hereditary disease of the gastrointestinal tract in which the body is intolerant to certain proteins found in grains, collectively known as gluten. Many people have celiac disease and don't know it. This can lead to serious complications.

Symptoms of celiac disease:

• weight loss, excessive thinness;
• diarrhea or constipation;
• pulling, throbbing pains in the abdomen, flatulence;
• joint pains;
• blister-like rashes on the skin and mucous membrane;
• constant fatigue;
• iron deficiency anemia.

Symptoms of celiac disease are manifested by eating foods made from wheat, rye and barley. Celiac disease can affect not only the small intestine, but also other organs. Autoimmune damage to intestines, skin, liver, joints, uterus, heart and other organs is possible.

The diagnosis of celiac disease is definitively confirmed or rejected by diagnostic tests for celiac disease:

serological blood tests (antibodies against tissue transglutaminase (Anti-tTG), anti-glia antibodies;
during a bowel biopsy.